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Isaac Pennington, died a prisoner in the Tower of London, 15 December 1661. Pennington or Penington, c.1584-1661, English politician, Lord Mayor of London, parliamentarian and regicide of King Charles I. Within a frame decorated with vignettes of skull and cross bones, chains and executioners axe, a man hanging from a gibbet at Tyburn, a condemned man on a sled, the Tower of London, Newgate Prison. Copperplate engraving by Robert Cooper from James Caulfields The High Court of Justice, London, 1820.