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John Robert Vane (March 29, 1927 - November 19. 2004) was an English pharmacologist. He worked as an assistant professor the Department of Pharmacology at Yale University and then took a post as a senior lecturer in the Institute of Basic Medical Sciences at the University of London in 1955. Vane held a post at the University of London for 18 years, progressing from senior lecturer to Professor of Experimental Pharmacology in 1966. During that time he developed certain bioassay techniques and focussed his research on both angiotensin-converting enzyme and the actions of aspirin, eventually leading to the understanding of the relationship between aspirin and the prostaglandins that earned him the Nobel Prize in Physiology or Medicine in 1982. He died in 2004 at the age of 77, from long-term complications arising from leg and hip fractures he sustained earlier that year.