Caption:
Alois Alzheimer (1864-1915). In 1906, German psychiatrist and neuropathologist Alois Alzheimer made a complete clinical and pathological description of presenile dementia, which came to be known as Alzheimer's disease, a progressive condition in which nerve cells in the brain degenerate. The inset photograph at top shows Auguste Deter (1850-1906), the first patient Alzheimer diagnosed with the disease. Below her is a micrograph from a 1911 Journal of Psychiatry and Neurology (Zeitschrift für die Gesamte Neurologie und Psychiatrie) showing neurofibrillary tangles in the brain nerve cells of a patient afflicted with the disease.