In this illustration, Alexander the Great emerges naked from the Cydnus River. The cold water makes him ill and he is seen later in his tent on the left, accepting help from his physician Philip, even though Philip has been accused of plotting his death. In the background, the Persian Sisinnes is beheaded for treason after failing to report his knowledge of an assassination attempt against Alexander. Alexander III of Macedon (356-323 BC), commonly known as Alexander the Great, was a Greek king who conquered the Persian Empire. This illustration was created between 1470-75 by the Flemish illustrator known as "Master of the Jardin de vertueuse consolation" and an assistant. Tempera colors, gold leaf, gold paint, and ink on parchment.