Capture Of Cacafuego, engraving by Friedrich Hulsius, 1626. The Spanish galleon Nuestra Senora de la Concepcion (Our Lady of the Immaculate Conception) was a 120 ton vessel that sailed the Peru - Panama route during the 16th century. This ship has earned a place in maritime history not only by virtue of being Sir Francis Drake's most famous prize, but also because of her colorful nickname, Cacafuego which translates into English as 'fireshitter'.